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Marlène Dreux

Researcher at École normale supérieure de Lyon

Publications -  58
Citations -  8808

Marlène Dreux is an academic researcher from École normale supérieure de Lyon. The author has contributed to research in topics: Virus & Viral replication. The author has an hindex of 27, co-authored 54 publications receiving 7377 citations. Previous affiliations of Marlène Dreux include University of Lyon & French Institute of Health and Medical Research.

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras.

TL;DR: A series of further chimeric genomes allowing production of infectious genotype (GT) 1a, 1b, 2a, and 3a particles are created, suggesting that determinants within the structural proteins govern kinetic and efficiency of virus assembly and release and an E1-specific antiserum capable of neutralizing infectivity of all HCV chimeras is described.
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Interplay between SARS-CoV-2 and the type I interferon response.

TL;DR: The potential benefits of a well-timed IFN-I treatment and strategies to boost pDC-mediated IFN responses during the early stages of viral infection are discussed.
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Structural basis of steroid hormone perception by the receptor kinase BRI1.

TL;DR: It is proposed that steroid binding to BRI1 generates a docking platform for a co-receptor that is required for receptor activation, providing insight into the activation mechanism of this highly expanded family of plant receptors that have essential roles in hormone, developmental and innate immunity signalling.
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An Interplay between Hypervariable Region 1 of the Hepatitis C Virus E2 Glycoprotein, the Scavenger Receptor BI, and High-Density Lipoprotein Promotes both Enhancement of Infection and Protection against Neutralizing Antibodies

TL;DR: It is demonstrated that infection of hepatocarcinoma cells by HCVpp is increased more than 10-fold by human serum factors, of which high-density lipoprotein (HDL) is a major component, and HVR1 new roles which are complementary in helping HCV to survive within its host.