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Paul A. Ney

Researcher at New York Blood Center

Publications -  63
Citations -  16743

Paul A. Ney is an academic researcher from New York Blood Center. The author has contributed to research in topics: Autophagy & Globin. The author has an hindex of 37, co-authored 63 publications receiving 14734 citations. Previous affiliations of Paul A. Ney include University of Tennessee Health Science Center & St. Jude Children's Research Hospital.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Nix is a selective autophagy receptor for mitochondrial clearance

TL;DR: Nix functions as an autophagy receptor, which mediates mitochondrial clearance after mitochondrial damage and during erythrocyte differentiation, and ablation of the Nix:LC3/GABARAP interaction retards mitochondrial clearance in maturing murine reticulocytes.
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NIX is required for programmed mitochondrial clearance during reticulocyte maturation

TL;DR: It is shown that mitochondrial clearance in reticulocytes requires the BCL2-related protein NIX (BNIP3L) and a BAX- and BAK-independent role for a BCL3-relatedprotein in development, indicating that NIX does not function through established proapoptotic pathways.
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Role of bnip3 and nix in cell death, autophagy, and mitophagy

TL;DR: Possible mechanisms by which BNIP3 and NIX induce cell death and mitophagy are discussed and the potential relationship between cell death pathways and autophagy in development and homeostasis is considered.