Ralph Feuer

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The clinical and economic challenges that these agents pose are reviewed, current knowledge of host–pathogen interactions are summarized and a few of the many outstanding questions that remain to be answered are highlighted.

TL;DR: The preferential detection of the lipidated form of LC3 protein (LC3 II) in released EMVs harboring infectious virus suggests that the autophagy pathway plays a crucial role in microvesicle shedding and virus release, similar to a process previously described as autophagosome-mediated exit without lysis observed during poliovirus replication.

TL;DR: The generation of a recombinant coxsackievirus B3 expressing the enhanced green fluorescent protein (eGFP) is described, which is used to mark and track infected cells in vitro and suggests that cell cycle status determines the distribution of CVB3 during acute infection and the persistence ofCVB3 in vivo may rely on infection of quiescent cells incapable of supporting viral replication.