scispace - formally typeset
H

Helmut Krämer

Researcher at University of Texas Southwestern Medical Center

Publications -  81
Citations -  9354

Helmut Krämer is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Endosome & Autophagy. The author has an hindex of 36, co-authored 76 publications receiving 8167 citations. Previous affiliations of Helmut Krämer include University of Tübingen & University of California, Los Angeles.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

The three operators of the lac operon cooperate in repression.

TL;DR: Under conditions where loop formation is impossible, occupation of O3 but not of O2 may lead to weak repression, which suggests that under these conditions CAP activation may be inhibited and that stopping transcription at O2 does not significantly contribute to repression.
Journal ArticleDOI

lac repressor forms loops with linear DNA carrying two suitably spaced lac operators.

TL;DR: Tetrameric lac repressor may bind to two lac operators on one DNA fragment and induce the intervening DNA to form a loop, which is favoured by correct phasing of the two Lac operators and a low concentration of both components of the reaction.
Journal ArticleDOI

Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine-kinase receptor

TL;DR: In the developing eye the sevenless-dependent internalization of bride of sevenless by the R7 precursor cell provides evidence for a direct interaction between these two proteins in vivo.
Journal ArticleDOI

Drosophila Vps16A is required for trafficking to lysosomes and biogenesis of pigment granules

TL;DR: It is demonstrated that Drosophila Vps16A is essential for lysosomal trafficking, and metazoans have two types of Vps-C complexes with non-redundant functions.