scispace - formally typeset
R

Ruth S. Slack

Researcher at University of Ottawa

Publications -  157
Citations -  24188

Ruth S. Slack is an academic researcher from University of Ottawa. The author has contributed to research in topics: Programmed cell death & Mitochondrion. The author has an hindex of 69, co-authored 147 publications receiving 21494 citations. Previous affiliations of Ruth S. Slack include Montreal Neurological Institute and Hospital & Ottawa Hospital Research Institute.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Caspase 3 activity is required for skeletal muscle differentiation

Pasan Fernando, +4 more
- 20 Aug 2002 - 
TL;DR: It is reported that skeletal muscle differentiation depends on the activity of the key apoptotic protease, caspase 3, and identified Mammalian Sterile Twenty-like kinase as a crucial caspases 3 effector in this cellular process.
Journal ArticleDOI

Role of AIF in caspase-dependent and caspase-independent cell death

Sean P. Cregan, +2 more
- 12 Apr 2004 - 
TL;DR: The role of Bcl family proteins and poly(ADP-ribose) polymerase-1 signaling in the regulation of these apoptotic pathways are examined and ongoing controversies in this field are addressed.
Journal ArticleDOI

Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

Sean P. Cregan, +10 more
- 05 Aug 2002 - 
TL;DR: It is demonstrated that p53 can induce neuronal cell death via a caspase-mediated process activated by apoptotic activating factor-1 (Apaf1) and via a delayed onset casp enzyme-independent mechanism, and that apoptosis-inducing factor (AIF) is an important factor involved in the regulation of this caspases-independent neuronal cellDeath.