scispace - formally typeset
K

Kim N. Green

Researcher at University of California, Irvine

Publications -  128
Citations -  20313

Kim N. Green is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Microglia & Alzheimer's disease. The author has an hindex of 51, co-authored 109 publications receiving 16772 citations. Previous affiliations of Kim N. Green include University of California, Berkeley & University of Leeds.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Intracellular amyloid-β in Alzheimer's disease

TL;DR: Although the classical view is that Aβ is deposited extracellularly, emerging evidence from transgenic mice and human patients indicates that this peptide can also accumulate intraneuronally, which may contribute to disease progression.
Journal ArticleDOI

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

TL;DR: Surprisingly, extensive treatment results in elimination of ∼99% of all microglia brain-wide, showing that microglian homeostasis in the adult brain are physiologically dependent upon CSF1R signaling.
Journal ArticleDOI

Intraneuronal Aβ Causes the Onset of Early Alzheimer’s Disease-Related Cognitive Deficits in Transgenic Mice

TL;DR: This study strongly implicates intraneuronal Abeta in the onset of cognitive dysfunction in the 3xTg-AD mice, and rescues the early cognitive deficits on a hippocampal-dependent task.
Journal ArticleDOI

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.

TL;DR: Interestingly, despite widespread and established Aß plaque and neurofibrillary tangle pathology, hippocampal neural stem cell transplantation rescues the spatial learning and memory deficits in aged 3xTg-AD mice.