Giovanna Elvira Granato

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: It is found that dioxin increased proliferation, as well as, activated cell death with autophagy, as the authors detected by increased amount of LC3-II, an autophagosome marker, which support the idea that TCDD in MDBK cells, may exert its action, in part, by enhancing cell proliferation, but also by modulating the incidence of induced celldeath with autophile.

TL;DR: Results showed that TCDD influences BHV-1 induced apoptosis through members of Bcl-2 family and up-regulating activation of caspases and influences the apoptotic pathway in MDBK cells infected with BHv-1.

TL;DR: The dioxin-dependent iron metabolism dysregulation herein described may be linked to cell-fate decision, supporting the hypothesis of a central connection among exposure to dioxins and the regulation of critical cellular processes.