Sandra K. Halonen

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The major clinical outcomes of congenital infection, chorioretinitis and encephalitis, and the possible association of infection of toxoplasmosis with neuropsychiatric disorders such as schizophrenia, are reviewed.

TL;DR: Cysts were found to occur almost exclusively in neurons throughout chronic infection of T. gondii and the intracellular localization of the cysts analyzed during the development and establishment of a chronic infection at 1, 2, and 6 months post infection.

TL;DR: A mechanism by which ER/PV fusion is a crucial event in PV disruption is postulated, as electron microscopy and immunofluorescence studies indicate that the host cell ER fuses with the PV prior to vacuolar disruption.

TL;DR: Findings associate nonprofessional APCs with the initial activation of CD8+ T cells during toxoplasmosis, and this phenomenon is dependent on the transporter associated with antigen processing and requires live T. gondii.