Caroline A. Whitehouse

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The mechanism for the exposure of peptide epitopes in BT20 and T47D cells is proposed to be the loss of core-2 branching leading to shorter, sialylated O-glycan chains.

TL;DR: In this article, established and emerging dosimetry methods are reviewed, which can be used immediately and retrospectively following external ionising radiation exposure, and individual characteristics of these techniques, their limitations and potential for further development are discussed, and their usefulness in specific exposure scenarios is discussed.

TL;DR: Even when C2GnT1 is expressed, the O-glycans added to MUC1 become core 1-dominated structures, provided expression of ST3Gal-I is increased as it is in breast cancer, which indicates a switch to core 2 structures.

TL;DR: In situ hybridization of primary breast tissue showed that a sialyltransferase (ST3Gal I), responsible for adding sialic acid to core 1 thereby terminating chain extension, is elevated in primary breast carcinomas when compared to normal or benign tissue.