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Marta Izquierdo

Researcher at Spanish National Research Council

Publications -  56
Citations -  6337

Marta Izquierdo is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Polytene chromosome & Gene. The author has an hindex of 22, co-authored 54 publications receiving 5376 citations. Previous affiliations of Marta Izquierdo include Autonomous University of Madrid & University of Edinburgh.

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation.

TL;DR: It is shown that intratumoral administration of Δ9-tetrahydrocannabinol and the synthetic cannabinoid agonist WIN-55,212-2 induced a considerable regression of malignant gliomas in Wistar rats and in mice deficient in recombination activating gene 2.
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Short interfering RNAs as a tool for cancer gene therapy

TL;DR: RNAi technology can be directed against cancer using a variety of strategies, including the inhibition of overexpressed oncogenes, blocking cell division by interfering with cyclin E and related genes or promoting apoptosis by suppressing antiapoptotic genes.
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Use of the 2A sequence from foot-and-mouth disease virus in the generation of retroviral vectors for gene therapy

TL;DR: The construction of retroviral plasmid vectors in which two genes are linked by a minimum of 96 nucleotides encoding the 2A sequence from the picornavirus foot-and-mouth disease virus are described.
Journal Article

Human malignant brain tumor response to herpes simplex thymidine kinase (HSVtk)/ganciclovir gene therapy.

TL;DR: Growing cells from human brain tumors have been treated in vitro and in vivo with murine therapeutic retroviral producer cells, which carried the potential suicide gene thymidine kinase from the herpes simplex virus.