scispace - formally typeset
Z

Zhen Wang

Researcher at Fudan University

Publications -  22
Citations -  4943

Zhen Wang is an academic researcher from Fudan University. The author has contributed to research in topics: Medicine & Cancer research. The author has an hindex of 11, co-authored 14 publications receiving 3887 citations. Previous affiliations of Zhen Wang include Fudan University Shanghai Medical College & Peking Union Medical College.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Estrogen regulates Hippo signaling via GPER in breast cancer.

Xin Zhou, +15 more
- 01 May 2015 - 
TL;DR: The studies revealed that GPER stimulation activates yes-associated protein 1 (YAP) and transcriptional coactivator with a PDZ-binding domain (TAZ) and plays a critical role in breast tumorigenesis.
Journal ArticleDOI

Thromboxane A2 Activates YAP/TAZ Protein to Induce Vascular Smooth Muscle Cell Proliferation and Migration

Xu Feng, +13 more
- 02 Sep 2016 - 
TL;DR: It is reported that TP signaling induces VSMC migration and proliferation through activating YAP/TAZ, two major downstream effectors of the Hippo signaling pathway, indicating YAP /TAZ as potential therapeutic targets for cardiovascular diseases.
Journal ArticleDOI

Glyceraldehyde-3-phosphate dehydrogenase is activated by lysine 254 acetylation in response to glucose signal.

Tingting Li, +13 more
- 07 Feb 2014 - 
TL;DR: It is reported that acetylation at lysine 254 (K254) increases GAPDH activity in response to glucose and is reversibly regulated by the acetyltransferase PCAF and the deacetylase HDAC5.
Journal ArticleDOI

Endothelin promotes colorectal tumorigenesis by activating YAP/TAZ

Zhen Wang, +10 more
- 01 May 2017 - 
TL;DR: Results indicate a critical role of the YAP/TAZ axis in ETAR signaling, and demonstrate that ETAR stimulates colon cell proliferation, migration, and tumorigenesis through the activation of YAP /TAZ, two transcription coactivators of the Hippo tumor suppressor pathway.