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Kyeong Sook Choi

Researcher at Ajou University

Publications -  109
Citations -  11218

Kyeong Sook Choi is an academic researcher from Ajou University. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 51, co-authored 105 publications receiving 9541 citations. Previous affiliations of Kyeong Sook Choi include National Institutes of Health & Seoul National University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics

Gi Bang Koo, +21 more
- 08 May 2015 - 
TL;DR: This work shows that programmed necrosis is activated in response to many chemotherapeutic agents and contributes to chemotherapy-induced cell death, and proposes that RIP3-deficient cancer patients may benefit from receiving hypomethylating agents to induce RIP3 expression prior to treatment with conventional Chemotherapeutics.
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Two distinct modes of cell death induced by doxorubicin: apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype.

Young-Woo Eom, +8 more
- 14 Jul 2005 - 
TL;DR: Results indicate that different doses of doxorubicin activate different regulatory mechanisms to induce either apoptosis or cell death through mitotic catastrophe.
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Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells.

Eun-Hee Kim, +6 more
- 01 Jul 2007 - 
TL;DR: It is clearly shows that superoxide anion generated by selenite triggers mitochondrial damage and subsequent mitophagy, leading to irreversible cell death in glioma cells.
Journal ArticleDOI

Autophagy and cancer.

Kyeong Sook Choi
- 29 Feb 2012 - 
TL;DR: The pharmacological and/or genetic inhibition of autophagy was recently shown to sensitize cancer cells to the lethal effects of various cancer therapies, suggesting that suppression of the autophagic pathway may represent a valuable sensitizing strategy for cancer treatments.