scispace - formally typeset
G

Gabriella Marfe

Researcher at University of Rome Tor Vergata

Publications -  46
Citations -  5716

Gabriella Marfe is an academic researcher from University of Rome Tor Vergata. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 20, co-authored 46 publications receiving 4723 citations. Previous affiliations of Gabriella Marfe include Sapienza University of Rome.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Efficient production by sperm-mediated gene transfer of human decay accelerating factor (hDAF) transgenic pigs for xenotransplantation

Marialuisa Lavitrano, +19 more
- 29 Oct 2002 - 
TL;DR: Results show that the SMGT approach to transgenesis provides an efficient procedure for studies involving large animal models and was functional based on in vitro experiments performed on peripheral blood mononuclear cells.
Journal ArticleDOI

Kaempferol induces apoptosis in two different cell lines via Akt inactivation, Bax and SIRT3 activation, and mitochondrial dysfunction.

Gabriella Marfe, +7 more
- 01 Mar 2009 - 
TL;DR: The study shows that the oxidative stress induced by kaempferol in K562 and U937 cell lines causes the inactivation of Akt and the activation of the mitochondrial phase of the apoptotic program with an increase of Bax and SIRT3, decrease of Bcl‐2, release of cytochrome c, caspase‐3 activation, and cell death.
Journal ArticleDOI

Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-κB

Marco Tafani, +10 more
- 01 Aug 2011 - 
TL;DR: Results show that, hypoxia can upregulate expression levels of membrane receptors that, by binding extracellular molecules eventually released by necrotic cells, contribute to the increased invasiveness of transformed tumor cells.
Journal ArticleDOI

Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models

Roberta De Rosa, +17 more
- 01 Jan 2013 - 
TL;DR: SphK1 contribution to resistance was supported by the demonstration that SphK 1 inhibition by N,N-dimethyl-sphingosine or silencing via siRNA in resistant cells restores sensitivity to cetuximab, whereas exogenous SphK1 overexpression in sensitive cells confers resistance to these agents.