Hyung Jun Ahn

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The superior efficiency of the siRNA/capsid nanocarrier complexes in RFP gene silencing, compared to untreated cells is demonstrated, providing an alternative approach to enhancing the stability of siRNA as well as to achieving targeted siRNA delivery.

TL;DR: By targeting this OA biomarker, the symptoms of the early and late stages of OA can be readily monitored, imaged, and analyzed in a rapid and efficient fashion, and this simple and highly efficient fluorogenic probe will assist in the clinical management of patients with OA.

TL;DR: Haluronic acid-labeled poly(d,l-lactide-co-glycolide) nanoparticle encapsulating both paclitaxel (PTX) and focal adhesion kinase (FAK) siRNA as a selective delivery system against chemoresistant ovarian cancer demonstrates the efficacy of a novel, selective, two-in-one delivery system to overcome chemoresistance in epithelial ovarian cancer.

TL;DR: This strategy allows the design of a platform technology for systemic delivery of siRNA to tumour sites, because RCT reaction, which enzymatically generates RNA polymers in multiple copy numbers at low cost, can lead to directly accessible routes to targeted and systemic delivery.