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Hong Jiang

Researcher at Central South University

Publications -  393
Citations -  23057

Hong Jiang is an academic researcher from Central South University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 51, co-authored 280 publications receiving 18722 citations. Previous affiliations of Hong Jiang include University of Texas at Austin & City University of New York.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

Vancheswaran Gopalakrishnan, +71 more
- 05 Jan 2018 - 
TL;DR: Examination of the oral and gut microbiome of melanoma patients undergoing anti-programmed cell death 1 protein (PD-1) immunotherapy suggested enhanced systemic and antitumor immunity in responding patients with a favorable gut microbiome as well as in germ-free mice receiving fecal transplants from responding patients.
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Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.

Pei Ling Chen, +43 more
- 01 Aug 2016 - 
TL;DR: It is demonstrated that adaptive immune signatures in tumor biopsy samples obtained early during the course of treatment are highly predictive of response to immune checkpoint blockade and also demonstrate differential effects on the tumor microenvironment induced by CTLA4 and PD-1 blockade.
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Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance

Whijae Roh, +39 more
- 01 Mar 2017 - 
TL;DR: Deep molecular profiling of melanoma patients treated with sequential checkpoint blockade demonstrated that a more clonal T cell repertoire was predictive of response to PD-1 but not CTLA-4 blockade, suggesting the potential utility of a combinatorial biomarker to optimize patient care with checkpoint blockade therapy.