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Stephan T. Stern

Researcher at Leidos

Publications -  59
Citations -  13010

Stephan T. Stern is an academic researcher from Leidos. The author has contributed to research in topics: Autophagy & Cancer. The author has an hindex of 25, co-authored 55 publications receiving 11216 citations. Previous affiliations of Stephan T. Stern include National Chemical Laboratory & Science Applications International Corporation.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

TL;DR: The significance of autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity as well as a growing body of literature suggesting that biopersistent nanom material can, in turn, negatively impact these pathways is highlighted.
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Nanotechnology safety concerns revisited.

TL;DR: The available data support the ability of the lung, gastrointestinal tract, and skin to act as a significant barrier to the systemic exposure of many nanomaterials and require a better understanding of exposure to further evaluate their risk.
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Detoxification of gold nanorods by treatment with polystyrenesulfonate.

TL;DR: Exchange of CTAB-laden PSS with fresh polyelectrolyte greatly improves biocompatibility, to the extent that 85 microg/mL of "CTAB-free" GNRs (the highest level evaluated) has comparable toxicity to a standard phosphate buffer solution.