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Francis V. Chisari

Researcher at Scripps Research Institute

Publications -  322
Citations -  57527

Francis V. Chisari is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Hepatitis B virus & Virus. The author has an hindex of 123, co-authored 322 publications receiving 54772 citations. Previous affiliations of Francis V. Chisari include University of Otago & University of Parma.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Robust hepatitis C virus infection in vitro

TL;DR: A simple yet robust HCV cell culture infection system based on the HCV JFH-1 molecular clone and Huh-7-derived cell lines that allows the production of virus that can be efficiently propagated in tissue culture is reported.
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Hepatitis B virus immunopathogenesis

TL;DR: Elucidation of the immunological and virological basis for HBV persistence may yield immunotherapeutic and antiviral strategies to terminate chronic HBV infection and reduce the risk of its life-threatening sequellae.
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Determinants of Viral Clearance and Persistence during Acute Hepatitis C Virus Infection

TL;DR: The virological and immunological features of hepatitis C virus (HCV) infection were studied weekly for 6 months after accidental needlestick exposure in five health care workers, four of whom developed acute hepatitis that progressed to chronicity while one subject cleared the virus.
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Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

TL;DR: Results demonstrate that noncytopathic antiviral mechanisms contribute to viral clearance during acute viral hepatitis by purging HBV replicative intermediates from the cytoplasm and covalently closed circular viral DNA from the nucleus of infected cells.