Xiang Bo Wan

Researcher at Sun Yat-sen University

Publications - 28

Citations - 5601

Xiang Bo Wan is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Nasopharyngeal neoplasm & Nasopharyngeal carcinoma. The author has an hindex of 18, co-authored 25 publications receiving 4576 citations. Previous affiliations of Xiang Bo Wan include Dalian Medical University.

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more

- 01 Apr 2012 -

Autophagy

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

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Elevated Beclin 1 expression is correlated with HIF-1alpha in predicting poor prognosis of nasopharyngeal carcinoma.

Xiang Bo Wan, +13 more

- 01 Apr 2010 -

Autophagy

TL;DR: It is demonstrated that high autophagic Beclin 1 expression was an inferior prognostic marker for NPC cells surviving from chemoradiotherapy, suggesting a novel therapeutic molecular target for NPC.

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Aurora kinase inhibitory VX-680 increases Bax/Bcl-2 ratio and induces apoptosis in Aurora-A-high acute myeloid leukemia.

Xue Fei Huang, +11 more

- 01 Mar 2008 -

Blood

TL;DR: It is found that expression of Aur-A was markedly elevated in bone marrow mononuclear cells obtained from a significant portion of de novo acute myeloid leukemia (AML) patients, and VX-680 enhanced the cytotoxic effect of the chemotherapeutic agent etoposide (VP16) on AML cells.

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