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Aimee L. Edinger

Researcher at University of California, Irvine

Publications -  75
Citations -  16768

Aimee L. Edinger is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Autophagy & Chemokine receptor. The author has an hindex of 39, co-authored 73 publications receiving 14870 citations. Previous affiliations of Aimee L. Edinger include University of Pennsylvania.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Death by design: apoptosis, necrosis and autophagy

Aimee L. Edinger, +1 more
- 01 Dec 2004 - 
TL;DR: This work has helped to define the function of and mechanism for programmed necrosis and the role of autophagy in cell survival and suicide and to suggest a possible mechanism for non-apoptotic death.
Journal ArticleDOI

Akt Maintains Cell Size and Survival by Increasing mTOR-dependent Nutrient Uptake

Aimee L. Edinger, +1 more
- 01 Jul 2002 - 
TL;DR: It is reported that growth factor withdrawal results in the loss of surface transporters for not only glucose but also amino acids, low-density lipoprotein, and iron, which creates a catabolic state characterized by atrophy and a decline in the mitochondrial membrane potential.
Journal ArticleDOI

Age-related myelin degradation burdens the clearance function of microglia during aging

Shima Safaiyan, +11 more
- 01 Aug 2016 - 
TL;DR: It is found that myelin pieces were gradually released from aging myelin sheaths and were subsequently cleared by microglia, leading to lysosomal storage and contributing to microglial senescence and immune dysfunction in aging.