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Kevin Moreau

Researcher at University of Cambridge

Publications -  41
Citations -  9571

Kevin Moreau is an academic researcher from University of Cambridge. The author has contributed to research in topics: Autophagy & Autophagosome. The author has an hindex of 24, co-authored 34 publications receiving 8040 citations. Previous affiliations of Kevin Moreau include University of Lille Nord de France & Pasteur Institute.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Regulation of Mammalian Autophagy in Physiology and Pathophysiology

Brinda Ravikumar, +18 more
- 01 Oct 2010 - 
TL;DR: This review focuses on mammalian autophagy, and an overview of the understanding of its machinery and the signaling cascades that regulate it is given, and the possibility of autophagic upregulation as a therapeutic approach for various conditions is considered.
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Plasma membrane contributes to the formation of pre-autophagosomal structures

Brinda Ravikumar, +4 more
- 01 Aug 2010 - 
TL;DR: It is shown in mammalian cells that the heavy chain of clathrin interacts with Atg16L1 and is involved in the formation of Atg 16L1-positive early autophagosome precursors, and the plasma membrane contributes directly to the formation.
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Diverse Autophagosome Membrane Sources Coalesce in Recycling Endosomes

Claudia Puri, +4 more
- 12 Sep 2013 - 
TL;DR: Starvation, a primordial autophagy activator, reduces membrane recycling from recycling endosomes and enhances mATG9-ATG16L1 vesicle fusion, which may fine-tune physiological autophagic responses.
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Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy

Eszter Zavodszky, +6 more
- 13 May 2014 - 
TL;DR: The PD-causing D620N mutation in VPS35 restricts Wash complex recruitment to endosomes, and reveals a novel role for the WASH complex in autophagosome formation, which is linked to several neurodegenerative diseases.