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Anna M. Krichevsky

Researcher at Brigham and Women's Hospital

Publications -  90
Citations -  23953

Anna M. Krichevsky is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: microRNA & Glioma. The author has an hindex of 44, co-authored 81 publications receiving 21058 citations. Previous affiliations of Anna M. Krichevsky include Rutgers University & Harvard University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

TL;DR: Tumour-derived microvesicles may provide diagnostic information and aid in therapeutic decisions for cancer patients through a blood test by incorporating an mRNA for a reporter protein into them, and it is demonstrated that messages delivered by microvesicle are translated by recipient cells.
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MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells.

TL;DR: It is shown that the highly malignant human brain tumor, glioblastoma, strongly over-expresses a specific miRNA, miR-21, which may contribute to the malignant phenotype by blocking expression of critical apoptosis-related genes.
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A microRNA array reveals extensive regulation of microRNAs during brain development

TL;DR: It is shown that an oligonucleotide DNA array can be successfully used for the simultaneous analysis of miRNA expression profiles from tissues or cells and provided a new tool for studying mi RNA expression in a variety of biological and pathobiological settings.
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miR‐21: a small multi‐faceted RNA

TL;DR: The aim of this study was to identify miR‐21 as a diagnostic and prognostic marker and potential therapeutic target for gliomas and investigate the mechanisms of elevation in cancer.