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Linda J. Bendall

Researcher at University of Sydney

Publications -  88
Citations -  10754

Linda J. Bendall is an academic researcher from University of Sydney. The author has contributed to research in topics: Bone marrow & Haematopoiesis. The author has an hindex of 38, co-authored 88 publications receiving 9544 citations. Previous affiliations of Linda J. Bendall include University of South Australia & Westmead Hospital.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide.

TL;DR: It is reported that mobilization of HPCs by GCSF coincides in vivo with the cleavage of the N-terminus of the chemokine receptor CXCR4 on H PCs resident in the BM and mobilized into the PB.
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Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells.

TL;DR: Exogenous Opn potently suppresses the proliferation of primitive HPCs in vitro, the physiologic relevance of which is demonstrated by the markedly enhanced cycling of HSC in Opn-/- mice.
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Matrix Metalloproteinase Activity Inactivates the CXC Chemokine Stromal Cell-derived Factor-1

TL;DR: The N-terminal processing of the CXC chemokines stromal cell-derived factor (SDF)-1α and β by MMP-2 is reported, suggesting that MMPs may be important regulatory proteases in attenuating SDF-1 function and point to a deep convergence of two important networks, chemokine and M MPs, to regulate leukocytic activity in vivo.
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Characterization of GMP-140 (P-selectin) as a circulating plasma protein.

TL;DR: Since it has been shown that fluid-phase GMP-140 is antiinflammatory and downregulates CD18- dependent neutrophil adhesion and respiratory burst, its presence in plasma may be of major importance in preventing the inadvertent activation of neutrophils in the circulation.