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Hesham M. Al-Younes

Researcher at University of Jordan

Publications -  27
Citations -  5187

Hesham M. Al-Younes is an academic researcher from University of Jordan. The author has contributed to research in topics: Chlamydia trachomatis & Chlamydophila pneumoniae. The author has an hindex of 13, co-authored 26 publications receiving 4236 citations. Previous affiliations of Hesham M. Al-Younes include Max Planck Society.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Epithelial Cells Infected with Chlamydophila pneumoniae (Chlamydia pneumoniae) Are Resistant to Apoptosis

Krishnaraj Rajalingam, +5 more
- 01 Dec 2001 - 
TL;DR: The data suggest a direct modulation of apoptotic pathways in epithelial cells by C. pneumoniae, the obligate intracellular pathogen that initiates infections in humans via the mucosal epithelia of the respiratory tract, which is resistant to apoptosis induced by treatment with drugs or by death receptor ligation.
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IFN-γ-Inducible Irga6 Mediates Host Resistance against Chlamydia trachomatis via Autophagy

Munir A. Al-Zeer, +4 more
- 26 Feb 2009 - 
TL;DR: Irga6 is identified as a necessary factor in conferring host resistance by remodelling a classically nonfusogenic intracellular pathogen to stimulate fusion with autophagosomes, thereby rerouting the intruder to the lysosomal compartment for destruction.
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Low iron availability modulates the course of Chlamydia pneumoniae infection

Hesham M. Al-Younes, +4 more
- 01 Jun 2001 - 
TL;DR: It is postulate that, for C. pneumoniae also, iron is an indispensable element and that Chlamydia may use iron transport pathways of the host by attracting TfR to the phagosome by attracting transferrin receptors around inclusions.
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Autophagy restricts Chlamydia trachomatis growth in human macrophages via IFNG-inducible guanylate binding proteins

Munir A. Al-Zeer, +4 more
- 01 Jan 2013 - 
TL;DR: In this paper, the authors identified hGBP1/2 as important resistance factors against C. trachomatis infection in IFNG-stimulated human macrophages.