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Meng-Chao Yao

Researcher at Academia Sinica

Publications -  92
Citations -  14795

Meng-Chao Yao is an academic researcher from Academia Sinica. The author has contributed to research in topics: Tetrahymena & Macronucleus. The author has an hindex of 48, co-authored 91 publications receiving 13318 citations. Previous affiliations of Meng-Chao Yao include National Taiwan University & National Defense Medical Center.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Book ChapterDOI

Isolation of micro- and macronuclei of Tetrahymena pyriformis.

TL;DR: This chapter discusses the isolation of micro- and macronuclei of Tetrahymena Pyriformis and suggests that these two nuclei may be used as a model system to explore the mechanisms whereby the same genetic information is maintained in different structural and functional states in eukaryotic cells.
Journal ArticleDOI

Comparison of the sequences of macro- and micronuclear DNA of Tetrahymena pyriformis

TL;DR: Findings place severe constraint on possible models concerning the structure of the Tetrahymena macronucleus, and are very different from the situation observed in Stylonychia where it has been suggested that only a small percentage of the sequences in micronuclei are present in significant amounts in macron nuclei.
Journal ArticleDOI

Programmed DNA deletion as an RNA-guided system of genome defense.

TL;DR: The process recognized and deleted a foreign gene integrated in a Tetrahymena chromosome, suggesting an unusual mechanism of genome surveillance and injection of double-stranded RNA into the cell at specific developmental stages triggers efficient deletion of the targeted genomic regions.