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Gilbert Di Paolo

Researcher at Columbia University Medical Center

Publications -  124
Citations -  19448

Gilbert Di Paolo is an academic researcher from Columbia University Medical Center. The author has contributed to research in topics: Endosome & Neurodegeneration. The author has an hindex of 57, co-authored 114 publications receiving 16373 citations. Previous affiliations of Gilbert Di Paolo include Columbia University & Yale University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Phosphoinositides in cell regulation and membrane dynamics

Gilbert Di Paolo, +1 more
- 12 Oct 2006 - 
TL;DR: Inositol phospholipids mediate acute responses, but also act as constitutive signals that help define organelle identity, and play a fundamental part in controlling membrane–cytosol interfaces.
Journal ArticleDOI

Essential Role of Phosphoinositide Metabolism in Synaptic Vesicle Recycling

Ottavio Cremona, +12 more
- 15 Oct 1999 - 
TL;DR: It is reported here that synaptojanin 1-deficient mice exhibit neurological defects and die shortly after birth, providing genetic evidence for a crucial role of phosphoinositide metabolism in synaptic vesicle recycling.
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Linking lipids to Alzheimer's disease: cholesterol and beyond

Gilbert Di Paolo, +1 more
- 01 May 2011 - 
TL;DR: Exploration of lipid dysregulation in AD and identification of novel therapeutic agents acting through relevant lipid pathways offers new and effective options for the treatment of this devastating disorder.
Journal ArticleDOI

Comparative lipidomic analysis of mouse and human brain with Alzheimer disease.

Robin B. Chan, +8 more
- 20 Jan 2012 - 
TL;DR: In this paper, a system-based approach was employed to determine the lipidome of brain tissues affected by Alzheimer disease using liquid chromatography-mass spectrometry to profile extracts from the prefrontal cortex, entorhinal cortex, and cerebellum of late-onset AD patients.