Mee-Len Chye

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Transgenic lines showed an increase in the level of total sterols up to 6-fold, probably because of an increased expression level of hmg1 mRNA and a corresponding increased enzymatic activity for HMGR, which strongly support the conclusion that plant HMGR is a key limiting enzyme in phytosterol biosynthesis.

TL;DR: Observations that recombinant ACBP3 binds PC, PE, and unsaturated acyl-CoAs in vitro and that AC BP3 overexpression enhances degradation of the autophagy (ATG)-related protein ATG8 and disrupts autophagosome formation suggest a role for ACBP 3 as a phospholipid binding protein involved in the regulation of leaf senescence by modulating membrane phospholIPid metabolism and ATG 8 stability in Arabidopsis.

TL;DR: The function of relevant genes in the MVA pathway that can be utilised in metabolic engineering is reviewed and future perspectives are presented, including the improvement in the production of phytosterols and other isoprenoid derivatives.

TL;DR: The significance of its ankyrin repeats in mediating protein-protein interactions by yeast two-hybrid analysis and in vitro protein-binding assays is investigated and it is shown that ACBP2 interacts with the A. thaliana ethylene-responsive element-binding protein AtEBP via its ank Kyrin repeats.