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Marjan Garmyn

Researcher at Katholieke Universiteit Leuven

Publications -  58
Citations -  6368

Marjan Garmyn is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Medicine & Apoptosis. The author has an hindex of 23, co-authored 48 publications receiving 5319 citations. Previous affiliations of Marjan Garmyn include Universitaire Ziekenhuizen Leuven.

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Ultraviolet radiation-induced apoptosis in keratinocytes: On the role of cytosolic factors

TL;DR: The response and role of mitogen-activated protein kinases in UVA and UVB radiation-induced signaling to apoptosis in keratinocytes and what is known about the role of the BCL-2 family of proteins are summarized.
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p38 mitogen-activated protein kinase regulates a novel, caspase-independent pathway for the mitochondrial cytochrome c release in ultraviolet B radiation-induced apoptosis.

TL;DR: It is shown that a sustained p38 MAPK activation contributes to the UVB-induced apoptosis by mediating the release of mitochondrial cytochrome c into the cytosol and that the initial cy tochrome c release is independent of caspase activity.
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1,25-Dihydroxyvitamin D3 inhibits ultraviolet B-induced apoptosis, Jun kinase activation, and interleukin-6 production in primary human keratinocytes.

TL;DR: Findings suggest the existence of a photoprotective effect of active vitamin D3 and create new perspectives for the pharmacological use of active Vitamin D compounds in the prevention of UVB‐induced skin damage and carcinogenesis.