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Lorianne S. Turner

Researcher at Francis Marion University

Publications -  12
Citations -  4969

Lorianne S. Turner is an academic researcher from Francis Marion University. The author has contributed to research in topics: Acid Ceramidase & Prostate cancer. The author has an hindex of 10, co-authored 12 publications receiving 4049 citations. Previous affiliations of Lorianne S. Turner include Medical University of South Carolina.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Acid ceramidase upregulation in prostate cancer cells confers resistance to radiation: AC inhibition, a potential radiosensitizer

Ayman Mahdy, +19 more
- 01 Mar 2009 - 
TL;DR: The current study on the effects of radiation on prostate cancer cells reveals that radiation programs an unpredicted resistance mechanism by upregulating acid ceramidase (AC), which is, in part, mediated by application of the therapy itself.
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The functional effects of acid ceramidase overexpression in prostate cancer progression and resistance to chemotherapy.

Antonio F. Saad, +14 more
- 01 Sep 2007 - 
TL;DR: AC is implicates as a critical regulator of PCa progression by affecting not only tumor cell proliferation and migration but also responses to drug therapy, suggesting AC as a potential therapeutic target in advanced PCa.
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Role of Acid Ceramidase in Resistance to FasL: Therapeutic Approaches Based on Acid Ceramidase Inhibitors and FasL Gene Therapy

Saeed Elojeimy, +15 more
- 01 Jul 2007 - 
TL;DR: It is shown that AC is over-expressed in 70% of head and neck squamous cell tumors compared with normal tissues, suggesting that this enzyme may play an important role in facilitating HNSCC growth and the combination of FasL gene therapy and LCL 204 may become a new treatment option for advanced-stageHead and neck cancer.
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Lysosomotropic acid ceramidase inhibitor induces apoptosis in prostate cancer cells.

David H. Holman, +11 more
- 12 Apr 2007 - 
TL;DR: Evidence is provided that treatment with molecules such as LCL204, which restore ceramide levels in PCa cells may serve as a new viable treatment option for PCa.