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Addanki P. Kumar

Researcher at University of Texas Health Science Center at San Antonio

Publications -  79
Citations -  7833

Addanki P. Kumar is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 30, co-authored 73 publications receiving 7093 citations. Previous affiliations of Addanki P. Kumar include University of Texas MD Anderson Cancer Center & University of Colorado Boulder.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Eugenol causes melanoma growth suppression through inhibition of E2F1 transcriptional activity

TL;DR: Examination of the mechanism of the antiproliferative action of eugenol in the human malignant melanoma cell line, WM1205Lu, showed that it arrests cells in the S phase of the cell cycle, suggesting that eugenols could be developed as an E2F-targeted agent for melanoma treatment.
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Regulation of BRCA1 expression by the Rb-E2F pathway.

TL;DR: It is demonstrated that the product of the RB1 gene, Rb, regulates the expression of the murine Brca1 and human BRCA1 genes through its ability to modulate E2F transcriptional activity.
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CD44 Expression Level and Isoform Contributes to Pancreatic Cancer Cell Plasticity, Invasiveness, and Response to Therapy.

TL;DR: PDAC cells expressing high levels of CD44s with a mesenchymal-like phenotype were highly invasive and developed gemcitabine resistance in vivo, suggesting initial targeting CD44 or reversing the CD44high phenotype may improve therapeutic response.