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Jayoung Choi

Researcher at University of Chicago

Publications -  24
Citations -  6468

Jayoung Choi is an academic researcher from University of Chicago. The author has contributed to research in topics: Viral replication & GTPase. The author has an hindex of 16, co-authored 24 publications receiving 5909 citations. Previous affiliations of Jayoung Choi include Washington University in St. Louis & KAIST.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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FoxH1 negatively modulates flk1 gene expression and vascular formation in zebrafish.

TL;DR: It is shown that FoxH1 binds to the flk1 endothelial enhancer in vitro and functions as a repressor forFlk1 transcription in cultured cells, and that Fox H1 is involved in vessel formation in zebrafish.
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The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy.

TL;DR: It is shown that the cassette of autophagy proteins involved in the conjugation of microtubule-associated protein 1 light chain 3 (LC3) to phosphatidylethanolamine, including Atg7, Atg3, and the Atg12- atg5-Atg16L1 complex play crucial roles in the control of T. gondii in vitro and in vivo.
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A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development

TL;DR: The finding of a mitochondrial matrix-targeted protein phosphatase 2C family member (PP2Cm) that regulates mitochondrial membrane permeability transition pore (MPTP) opening and is essential for cell survival, embryonic development, and cardiac function is reported.
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Armed Response: How Dying Cells Influence T-Cell Functions

TL;DR: This review discusses how the decision is made by focusing on the biochemical process of cell death and how its key components can influence both tolerance and immunity.