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Deepti S. Wilkinson

Researcher at Discovery Institute

Publications -  11
Citations -  5937

Deepti S. Wilkinson is an academic researcher from Discovery Institute. The author has contributed to research in topics: Autophagy & Kinase. The author has an hindex of 10, co-authored 11 publications receiving 5426 citations. Previous affiliations of Deepti S. Wilkinson include Sanford-Burnham Institute for Medical Research & Salk Institute for Biological Studies.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Fine-Tuning of Drp1/Fis1 Availability by AKAP121/Siah2 Regulates Mitochondrial Adaptation to Hypoxia

Hyungsoo Kim, +8 more
- 18 Nov 2011 - 
TL;DR: Through modulating Fis1/Drp1 complex availability, Siah2 is identified as a key regulator of hypoxia-induced mitochondrial fission and its physiological significance in ischemic injury and nematode life span.
Journal ArticleDOI

Phosphorylation of LC3 by the Hippo kinases STK3/STK4 is essential for autophagy.

Deepti S. Wilkinson, +10 more
- 08 Jan 2015 - 
TL;DR: It is concluded that phosphorylation of LC3 by STK3/STK4 is an essential step in the autophagy process and it is proposed that pharmacological agents targeting this regulatory circuit hold therapeutic potential.
Journal ArticleDOI

A Direct Intersection between p53 and Transforming Growth Factor β Pathways Targets Chromatin Modification and Transcription Repression of the α-Fetoprotein Gene

Deepti S. Wilkinson, +8 more
- 01 Feb 2005 - 
TL;DR: The purified oncoprotein SnoN functions as a corepressor of the tumor suppressor p53 in the regulation of the hepatic α-fetoprotein (AFP) tumor marker gene and supports a model of cooperativity between p53 and TGF-β effectors in chromatin modification and transcription repression of an oncodevelopmental tumor marker genes.
Journal Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2459 more
- 01 Jan 2016 -