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Karin von Schwarzenberg

Researcher at Ludwig Maximilian University of Munich

Publications -  20
Citations -  6026

Karin von Schwarzenberg is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Cancer cell & Programmed cell death. The author has an hindex of 15, co-authored 18 publications receiving 5507 citations. Previous affiliations of Karin von Schwarzenberg include University of Bonn & University of Tübingen.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

The V-ATPase-inhibitor Archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1

TL;DR: The results indicate that archazolid effectively decreases metastatic dissemination of breast tumors by impairing the trafficking and spatially restricted activation of EGFR and Rho-GTPase Rac1, which are pivotal for directed movement of cells.
Journal ArticleDOI

Mode of Cell Death Induction by Pharmacological Vacuolar H+-ATPase (V-ATPase) Inhibition

TL;DR: It is concluded that archazolid leads to energy stress which activates adaptive mechanisms like autophagy mediated by HIF1α and finally leads to apoptosis which is proposed as a promising drugable target in cancer therapy caught up at the interplay of apoptosis, Autophagy, and cellular/metabolic stress.
Journal ArticleDOI

Targeting apoptosis pathways by natural compounds in cancer: marine compounds as lead structures and chemical tools for cancer therapy.

TL;DR: Natural compounds derived from marine organisms and their synthetic derivates are an important source for new therapeutics for single agent or combined therapy with other chemotherapeutics to support the struggle against cancer.
Journal Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2459 more
- 01 Jan 2016 -