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Junko Oshima

Junko Oshima

Researcher at University of Washington

Publications - 147

Citations - 17196

Junko Oshima is an academic researcher from University of Washington. The author has contributed to research in topics: Werner syndrome & Gene. The author has an hindex of 51, co-authored 136 publications receiving 16043 citations. Previous affiliations of Junko Oshima include Veterans Health Administration & University of California, Berkeley.

Papers

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

- 21 Jan 2016 -

Autophagy

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TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

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Journal ArticleDOI

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

Ephrat Levy-Lahad,Wilma Wasco,Parvoneh Poorkaj,Donna M. Romano,Junko Oshima,Warren H. Pettingell,Chang En Yu,P. D. Jondro,Stephen D. Schmidt,Kai Wang,Annette C. Crowley,Ying-Hui Fu,Suzanne Y. Guénette,David J. Galas,Ellen Nemens,Ellen M. Wijsman,Thomas D. Bird,Gerard D. Schellenberg,Rudolph E. Tanzi +18 moreVeterans Health Administration,Harvard University,University of Washington

- 18 Aug 1995 -

Science

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TL;DR: The presence of missense mutations in AD subjects in two highly similar genes strongly supports the hypothesis that mutations in both are pathogenic.

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Journal ArticleDOI

Positional Cloning of the Werner's Syndrome Gene

Chang En Yu,Junko Oshima,Ying-Hui Fu,Ellen M. Wijsman,Fuki M. Hisama,Reid S. Alisch,Shellie Matthews,Jun Nakura,Tetsuro Miki,Samir Ouais,George M. Martin,John Mulligan,Gerard D. Schellenberg +12 moreUniversity of Washington,Yale University,Osaka University

- 12 Apr 1996 -

Science

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TL;DR: The identification of a mutated putative helicase as the gene product of the WS gene suggests that defective DNA metabolism is involved in the complex process of aging in WS patients.

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Journal ArticleDOI

The Werner syndrome protein is a DNA helicase.

Matthew D. Gray,Jiang Cheng Shen,Ashwini S. Kamath-Loeb,A. Blank,Bryce L. Sopher,George M. Martin,Junko Oshima,Lawrence A. Loeb +7 moreUniversity of Washington

- 01 Sep 1997 -

Nature Genetics

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TL;DR: It is reported that the Werner syndrome protein does indeed catalyze DNA unwinding and is homologous to members of the RecQ family of DNA helicases.

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LMNA mutations in atypical Werner's syndrome

Lishan Chen,Lin Lee,Brian A. Kudlow,Heloísa G. dos Santos,Olav Sletvold,Yousef Shafeghati,Eleanor G. Botha,Abhimanyu Garg,Nancy B. Hanson,George M. Martin,I. Saira Mian,Brian K. Kennedy,Junko Oshima +12 moreUniversity of Washington,Norwegian University of Science and Technology,Emory University,University of Texas Southwestern Medical Center,Lawrence Berkeley National Laboratory

- 08 Nov 2003 -

The Lancet

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TL;DR: The findings indicate that Werner's syndrome is molecularly heterogeneous, and a subset of the disorder can be judged a laminopathy.

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