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Valentín Ceña

Researcher at University of Castilla–La Mancha

Publications -  133
Citations -  11040

Valentín Ceña is an academic researcher from University of Castilla–La Mancha. The author has contributed to research in topics: Apoptosis & Chromaffin cell. The author has an hindex of 40, co-authored 127 publications receiving 9864 citations. Previous affiliations of Valentín Ceña include National Institutes of Health & French Institute of Health and Medical Research.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Sequential Treatment of SH‐SY5Y Cells with Retinoic Acid and Brain‐Derived Neurotrophic Factor Gives Rise to Fully Differentiated, Neurotrophic Factor‐Dependent, Human Neuron‐Like Cells

TL;DR: This model may be useful to perform large‐scale biochemical and molecular studies due to its susceptibility to genetic manipulation and the availability of an unlimited amount of cells.
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D1 but not D5 Dopamine Receptors Are Critical for LTP, Spatial Learning, and LTP-Induced arc and zif268 Expression in the Hippocampus

TL;DR: The results indicate that D(1)R but not D(5)R are critical for hippocampal LTP and for the induction of Zif268 and Arc, proteins required for the transition from E-LTP to L-L TP and for memory consolidation in mammals.
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Endocytosis: The Nanoparticle and Submicron Nanocompounds Gateway into the Cell

TL;DR: This review covers the proposed pathways involved in the cellular uptake of different NPs and submicron particles types as well as the role that some of the physicochemical nanoparticle characteristics play in the uptake pathway preferentially used by the nanoparticles to gain access and deliver their cargo inside the cell.
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Adenosine released by astrocytes contributes to hypoxia‐induced modulation of synaptic transmission

TL;DR: It is concluded that during hypoxia, astrocytes contribute to regulate the excitatory synaptic transmission through the release of adenosine, which acting on A1Adenosine receptors reduces presynaptic transmitter release and serves as a protective mechanism by down regulating the synaptic activity level during demanding conditions such as transient Hypoxia.