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Karla Kirkegaard

Researcher at Stanford University

Publications -  111
Citations -  16652

Karla Kirkegaard is an academic researcher from Stanford University. The author has contributed to research in topics: RNA & RNA-dependent RNA polymerase. The author has an hindex of 55, co-authored 107 publications receiving 15555 citations. Previous affiliations of Karla Kirkegaard include Massachusetts Institute of Technology & Harvard University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Subversion of cellular autophagosomal machinery by RNA viruses.

William T. Jackson, +6 more
- 26 Apr 2005 - 
TL;DR: It is argued that these double-membraned structures provide membranous supports for viral RNA replication complexes, possibly enabling the nonlytic release of cytoplasmic contents, including progeny virions, from infected cells.
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The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus.

J. Antonio Gomez, +8 more
- 14 Feb 2013 - 
TL;DR: An enhancer-like lncRNA termed NeST is shown to be causal for all phenotypes conferred by murine viral susceptibility locus Tmevp3, and regulates epigenetic marking of IFN-γ-encoding chromatin, expression of IFn-γ, and susceptibility to a viral and a bacterial pathogen.
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Remodeling the Endoplasmic Reticulum by Poliovirus Infection and by Individual Viral Proteins: an Autophagy-Like Origin for Virus-Induced Vesicles

David Suhy, +2 more
- 01 Oct 2000 - 
TL;DR: Poliovirus-induced vesicles derive from the ER by the action of viral proteins 2BC and 3A by a mechanism that excludes resident host proteins, which is consistent with an autophagic origin for these membranes.
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The mechanism of RNA recombination in poliovirus.

Karla Kirkegaard, +1 more
- 07 Nov 1986 - 
TL;DR: The results strongly support a copy choice mechanism for RNA recombination, in which the viral RNA polymerase switches templates during negative strand synthesis.