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Monique Bernard

Researcher at Université de Montréal

Publications -  20
Citations -  9361

Monique Bernard is an academic researcher from Université de Montréal. The author has contributed to research in topics: Autophagy & Blood–brain barrier. The author has an hindex of 15, co-authored 20 publications receiving 8428 citations. Previous affiliations of Monique Bernard include Center for Excellence in Education.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation.

TL;DR: It is shown that TH17 lymphocytes transmigrate efficiently across BBB-ECs, highly express granzyme B, kill human neurons and promote central nervous system inflammation through CD4+ lymphocyte recruitment and that IL-17 and IL-22 disrupt BBB tight junctions in vitro and in vivo.
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The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

TL;DR: It is shown that astrocytes secrete Sonic hedgehog and that BBB ECs express Hedgehog (Hh) receptors, which together promote BBB formation and integrity during embryonic development and adulthood.
Journal ArticleDOI

Preferential recruitment of interferon-γ-expressing TH17 cells in multiple sclerosis

TL;DR: This study sought to evaluate the frequency of IFN‐γ–expressing TH17 lymphocytes in MS and EAE, and study their recruitment into the central nervous system (CNS).

Preferential Recruitment of Interferon-- Expressing T H 17 Cells in Multiple Sclerosis

TL;DR: In this paper, the authors evaluated the role of interferon (IFN)-producing T helper (TH) 1 and interleukin (IL)-17-expressing TH17 lymphocytes in multiple sclerosis (MS) and its animal model, experimental allergic encephalomyelitis (EAE).