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Alfonso Schiavi

Researcher at University of Düsseldorf

Publications -  32
Citations -  6094

Alfonso Schiavi is an academic researcher from University of Düsseldorf. The author has contributed to research in topics: Mitochondrion & Caenorhabditis elegans. The author has an hindex of 14, co-authored 27 publications receiving 5484 citations. Previous affiliations of Alfonso Schiavi include Leibniz Association & University of Rome Tor Vergata.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Iron-Starvation-Induced Mitophagy Mediates Lifespan Extension upon Mitochondrial Stress in C. elegans.

Alfonso Schiavi, +14 more
- 20 Jul 2015 - 
TL;DR: The findings indicate that mitophagy induction is part of an adaptive iron starvation response induced as a protective mechanism against mitochondrial stress, thus suggesting novel potential therapeutic strategies for the treatment of mitochondrial-associated, age-related disorders.
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p53/CEP-1 Increases or Decreases Lifespan, Depending on Level of Mitochondrial Bioenergetic Stress

Natascia Ventura, +6 more
- 01 Aug 2009 - 
TL;DR: It is found that cep‐1 is required to extend longevity in response to mild suppression of several bioenergetically relevant mitochondrial proteins, including frataxin – the protein defective in patients with Friedreich’s Ataxia.
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The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species

Didac Carmona-Gutierrez, +48 more
- 19 Feb 2019 - 
TL;DR: It is demonstrated that DMC extends lifespan and promotes health in multiple organisms by inducing autophagy and is identified in the plant Angelica keiskei koidzumi, to which longevity- and health-promoting effects are ascribed in Asian traditional medicine.
Journal Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2459 more
- 01 Jan 2016 -