scispace - formally typeset
J

Joëlle Wiels

Researcher at Institut Gustave Roussy

Publications -  77
Citations -  8627

Joëlle Wiels is an academic researcher from Institut Gustave Roussy. The author has contributed to research in topics: Antigen & Apoptosis. The author has an hindex of 33, co-authored 73 publications receiving 7986 citations. Previous affiliations of Joëlle Wiels include Centre national de la recherche scientifique & University of Paris-Sud.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal Article

Apoptosis Induced in Burkitt's Lymphoma Cells via Gb3/CD77, a Glycolipid Antigen

Marianne Mangeney, +5 more
- 01 Nov 1993 - 
TL;DR: It is shown that verotoxin, also called Shiga-like toxin, induces cell death in Gb3/CD77(+) Burkitt's lymphoma cells, not only by inhibiting protein synthesis as classically described but also through an additional mechanism, namely apoptosis.
Journal ArticleDOI

A glycolipid antigen associated with Burkitt lymphoma defined by a monoclonal antibody.

E Nudelman, +7 more
- 29 Apr 1983 - 
TL;DR: Chemical analysis of various Burkitt lymphoma cell lines revealed that the Burkittymphoma cells contained more than 100 times as much of the glycolipid antigen as was found in other human lymphoma and leukemia cell lines.
Journal ArticleDOI

Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins.

Tetsuya Okuda, +10 more
- 14 Apr 2006 - 
TL;DR: Tissue damage with edema, congestion, and cytopathic changes was observed, indicating that Gb3/CD77 (and its derivatives) exclusively function as a receptor for VTs in vivo, suggesting that basal Gb 3/ CD77 levels are sufficient for lethal effects of VTs.
Journal ArticleDOI

CD77: an antigen of germinal center B cells entering apoptosis.

Marianne Mangeney, +4 more
- 01 May 1991 - 
TL;DR: An extensive phenotypic and functional characterization of the tonsillar CD77+ B lymphocytes suggest that the CD77 molecule defines a B lymphocyte maturation pathway, specific for germinal center, where the cells undergo programmed cell death.