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Norbert Frey

Researcher at University of Kiel

Publications -  82
Citations -  8258

Norbert Frey is an academic researcher from University of Kiel. The author has contributed to research in topics: Heart failure & Cardiomyopathy. The author has an hindex of 26, co-authored 82 publications receiving 7184 citations. Previous affiliations of Norbert Frey include University Hospital Heidelberg & Heidelberg University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

Dan E. Arking, +260 more
- 01 Aug 2014 - 
TL;DR: In this paper, the authors identified 35 common variant loci associated with QT interval that collectively explain ∼8-10% of QT-interval variation and highlight the importance of calcium regulation in myocardial repolarization.
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RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction

Mark Luedde, +19 more
- 15 Jul 2014 - 
TL;DR: It is shown that RIP3-dependent necroptosis modulates post-ischaemic adverse remodelling in a mouse model of MI, and this novel signalling pathway may be an attractive target for future therapies that aim to limit the adverse consequences of myocardial ischaemia.
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Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.

Joana P. Bernardes, +165 more
- 15 Dec 2020 - 
TL;DR: The study demonstrates broad cellular effects of SARS-CoV-2 infection beyond classical immune cells and may serve as an entry point to develop biomarkers and targeted treatments of patients with COVID-19.
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Mechanisms of disease: hypertrophic cardiomyopathy

Norbert Frey, +2 more
- 01 Feb 2012 - 
TL;DR: Several potential pathways are discussed, which include altered calcium cycling and sarcomeric calcium sensitivity, increased fibrosis, disturbed biomechanical stress sensing, and impaired cardiac energy homeostasis, which could result in greater specificity and success of therapies for patients with HCM.