Albert Haas

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The antimicrobial mode of action of chitosan is investigated using a combination of approaches, including in vitro assays, killing kinetics, cellular leakage measurements, membrane potential estimations, and electron microscopy, in addition to transcriptional response analysis, and a possible mechanism for chitOSan's activity is postulated.

TL;DR: It is reported thatSec17p, Sec18p, and ATP are only needed for an early stage of the reaction that results in Sec17p release, and may function in a predocking stage ofThe reaction, rather than in bilayer fusion per se.

TL;DR: Typical v- and t-SNAREs are identified on the yeast vacuolar membrane, demonstrating that docking is mediated by cognate SNAREs on the two organelle membranes.

TL;DR: Research into phagosome biogenesis has flourished in recent years – the purpose of this review is to give a glimpse of where this research stands, with emphasis on the cell biology of macrophage phagosomes.