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Markus A. Rüegg

Researcher at University of Basel

Publications -  189
Citations -  22636

Markus A. Rüegg is an academic researcher from University of Basel. The author has contributed to research in topics: Agrin & Neuromuscular junction. The author has an hindex of 69, co-authored 184 publications receiving 20460 citations. Previous affiliations of Markus A. Rüegg include Anschutz Medical Campus & Institut national de la recherche agronomique.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

Estela Jacinto, +6 more
- 01 Nov 2004 - 
TL;DR: Two distinct TOR complexes constitute a primordial signalling network conserved in eukaryotic evolution to control the fundamental process of cell growth.
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Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

C. Florian Bentzinger, +12 more
- 05 Nov 2008 - 
TL;DR: It is demonstrated that muscle mTORC1 has an unexpected role in the regulation of the metabolic properties and that its function is essential for life.
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Neuropathology in Mice Expressing Human α-Synuclein

Herman van der Putten, +14 more
- 15 Aug 2000 - 
TL;DR: Thy1 transgene expression of wild-type human α-synuclein resulted in similar pathological changes, thus supporting a central role for mutant and wild- type α- Synuclein in familial and idiotypic forms of diseases with neuronal α- synucleinopathy and Lewy pathology.
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Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.

Asami Hagiwara, +9 more
- 02 May 2012 - 
TL;DR: Mammalian target of rapamycin complex 2 regulates hepatic glucose and lipid metabolism via insulin-induced Akt signaling to control whole-body metabolic homeostasis and has implications for emerging drug therapies that target mTORC2.