Ayesha N. Shajahan-Haq

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Endocrine resistant cells overexpress MYC and are better adapted to withstand periods of glucose deprivation and can use glutamine in the short term to maintain adequate metabolism to support cell survival.

TL;DR: In this article, a mathematical model of cell fate decisions mediated by autophagy is proposed to integrate existing knowledge about this decision process into a rigorous, analytical framework, which is consistent with existing quantitative measurements of autophag and apoptosis in rat kidney proximal tubular cells responding to cisplatin-induced stress.