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Kelly S. Doran

Researcher at University of Colorado Denver

Publications -  127
Citations -  11622

Kelly S. Doran is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Streptococcus agalactiae & Medicine. The author has an hindex of 40, co-authored 103 publications receiving 10174 citations. Previous affiliations of Kelly S. Doran include University of California, San Diego & San Diego State University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Bacteriophage adhering to mucus provide a non-host-derived immunity.

Jeremy J. Barr, +12 more
- 25 Jun 2013 - 
TL;DR: It is shown that phage-to-bacteria ratios were increased, relative to the adjacent environment, on all mucosal surfaces sampled, ranging from cnidarians to humans, and that this increase in phage abundance is mucus dependent and protects the underlying epithelium from bacterial infection.
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Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts

Jon Sin, +9 more
- 22 Feb 2016 - 
TL;DR: Respirometry reveals that the constituents of these newly established mitochondrial networks are better primed for OXPHOS and are more tightly coupled than those in myoblasts, which highlights the integral role of autophagy and mitophagy in myogenic differentiation.
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Coxsackievirus B exits the host cell in shed microvesicles displaying autophagosomal markers.

Scott M. Robinson, +19 more
- 10 Apr 2014 - 
TL;DR: The preferential detection of the lipidated form of LC3 protein (LC3 II) in released EMVs harboring infectious virus suggests that the autophagy pathway plays a crucial role in microvesicle shedding and virus release, similar to a process previously described as autophagosome-mediated exit without lysis observed during poliovirus replication.
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Group B streptococcal β-hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis

Kelly S. Doran, +2 more
- 01 Sep 2003 - 
TL;DR: Using oligonucleotide microarrays, it is found that GBS infection of human brain microvascular endothelial cells (HBMEC) induced a highly specific and coordinate set of genes including IL-8, Groalpha, Grobeta, IL-6, GM-CSF, myeloid cell leukemia sequence-1 (Mcl-1), and ICAM-1, which act to orchestrate neutrophil recruitment, activation, and enhanced survival.