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Mario Fabri

Researcher at University of Cologne

Publications -  88
Citations -  7229

Mario Fabri is an academic researcher from University of Cologne. The author has contributed to research in topics: Medicine & Cathelicidin. The author has an hindex of 23, co-authored 65 publications receiving 6404 citations. Previous affiliations of Mario Fabri include University of California, Los Angeles & Max Planck Society.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Vitamin D Is Required for IFN-γ–Mediated Antimicrobial Activity of Human Macrophages

Mario Fabri, +23 more
- 12 Oct 2011 - 
TL;DR: The authors found that cells from the adaptive immune system—T cells—governed bacterial control by releasing the cytokine interferon-γ (IFN-γ), which then activated infected macrophages, inciting the cells to attack the invading M. tuberculosis.
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T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism.

Kristina Edfeldt, +10 more
- 28 Dec 2010 - 
TL;DR: The ability of T-cell cytokines to differentially control monocyte vitamin D metabolism represents a mechanism by which cell-mediated immune responses can regulate innate immune mechanisms to defend against microbial pathogens.
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Local Tumor Treatment in Combination with Systemic Ipilimumab Immunotherapy Prolongs Overall Survival in Patients with Advanced Malignant Melanoma.

Sebastian Theurich, +18 more
- 02 Sep 2016 - 
TL;DR: The data suggest that the addition of LPT to ipilimumab is safe and effective in patients with metastatic melanoma irrespective of clinical disease characteristics and known risk factors.
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Abelson tyrosine kinase controls phagosomal acidification required for killing of Mycobacterium tuberculosis in human macrophages.

Heiko Bruns, +8 more
- 15 Oct 2012 - 
TL;DR: It is demonstrated that Abl tyrosine kinase, a master switch for cell growth and trafficking of intracellular organelles, controls the acidification of lysosomes in human macrophages and provides evidence that the regulation occurs on the level of the vacuolar-type H+-adenosine triphosphatase.