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Craig Blackstone

Researcher at National Institutes of Health

Publications -  137
Citations -  19984

Craig Blackstone is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Hereditary spastic paraplegia & Endoplasmic reticulum. The author has an hindex of 60, co-authored 130 publications receiving 18219 citations. Previous affiliations of Craig Blackstone include United States Department of Health and Human Services & Johns Hopkins University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

TL;DR: A role for calcineurin-dependent translocation of the profission dynamin related protein 1 (Drp1) to mitochondria in dysfunction-induced fragmentation is shown and it is shown that fragmentation of depolarized mitochondria depends on a loop involving sustained Ca2+ rise, activation of calcineURin, and dephosphorylation of Drp1 and its translocation to the organelle.
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Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology.

TL;DR: Protein phosphorylation at Ser637 results in clear alterations in Drp1 function and mitochondrial morphology that are likely involved in dynamic regulation of mitochondrial division in cells.
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AMPA glutamate receptor subunits are differentially distributed in rat brain

TL;DR: It is suggested that specific neurons and glial cells selectively express glutamate receptors composed of different subunit combinations and the co-expression of all AMPA receptor subunits within individual cells may not be obligatory for the functions of this glutamate receptor in vivo.
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Cellular localization of a metabotropic glutamate receptor in rat brain

TL;DR: In rat brain, the cellular localization of a phosphoinositide-linked metabotropic glutamate receptor (mGluR1 alpha) was demonstrated using antibodies that recognize the C-terminus of the receptor.