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David J. Reiner

Researcher at Texas A&M Health Science Center

Publications -  50
Citations -  7273

David J. Reiner is an academic researcher from Texas A&M Health Science Center. The author has contributed to research in topics: Caenorhabditis elegans & Gene. The author has an hindex of 17, co-authored 42 publications receiving 6538 citations. Previous affiliations of David J. Reiner include Lanzhou University & Texas A&M University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination

Daniel J. Dickinson, +4 more
- 01 Oct 2013 - 
TL;DR: A method to edit the C. elegans genome using the clustered, regularly interspersed, short palindromic repeats (CRISPR) RNA-guided Cas9 nuclease and homologous recombination and it is demonstrated that Cas9 is able to induce DNA double-strand breaks with specificity for targeted sites.
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Diverse behavioural defects caused by mutations in Caenorhabditis elegans unc-43 CaM Kinase II

David J. Reiner, +3 more
- 11 Nov 1999 - 
TL;DR: It is reported that unc-43 encodes the only Caenorhabditis elegans CaMKII, and mutations in the unc-103 potassium channel gene suppress a gain-of-function phenotype of unc- 43 in one tissue without affecting other tissues; thus, UNC-103 may be a tissue-specific target of CaMK II in vivo.
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The RalGEF-Ral Effector Signaling Network: The Road Less Traveled for Anti-Ras Drug Discovery:

Nicole F. Neel, +5 more
- 01 Mar 2011 - 
TL;DR: The evidence for the importance of the Ras-like (Ral) small GTPases in cancer and possible directions for therapeutic inhibition of aberrant Ral activation and signaling are summarized.
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Ral and Rheb GTPase Activating Proteins Integrate mTOR and GTPase Signaling in Aging, Autophagy, and Tumor Cell Invasion

Timothy D. Martin, +6 more
- 23 Jan 2014 - 
TL;DR: An unexpected crosstalk and integration of the Ral and mTOR signaling networks is identified, which caused mTORC1-dependent pancreatic tumor cell invasion and caused RalB-selective activation and Sec5- and exocyst-dependent engagement of mTORCs and suppression of autophagy.