Maria Beatrice Morelli

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: It is demonstrated that co-administration of cytotoxic agents together with the TRPV2 agonist CBD increases drug uptake and parallelly potentiates cytot toxic activity in human glioma cells.

TL;DR: A novel connection between ATM DNA damage response pathway and Fas/CD95-mediated intrinsic and extrinsic apoptotic pathways triggered by TRPV1 stimulation on UC cells is described.

TL;DR: Current knowledge of interactions between immune cells and PRRs and ion channels of TRP families with PAMPs and DAMPs are summarized to provide new insights into the pathogenesis of inflammatory diseases.

TL;DR: It is demonstrated that cannabidiol by activating transient receptor potential vanilloid‐2 (TRPV2) triggers GSCs differentiation activating the autophagic process and inhibits G SCs proliferation and clonogenic capability, and CBD and carmustine in combination overcome the high resistance of GSCS to BCNU treatment, by inducing apoptotic cell death.