Heidi Kiil Blomhoff

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Substantial progress has been made in the understanding of retinoid metabolism and function, and central aspects of vitamin A absorption, enzymatic oxidation of all-trans retinol to all-Trans retinal and all- trans retinoic acid, and esterification ofall-trans Retinol have been clarified.

TL;DR: It is concluded that apoptosis is a regulated phenomenon in resting human B cells, and TGF-beta and cAMP may inhibit B cell responses not only by blocking cell cycle progression in activated cells, but also by inducing apoptosis in resting cells.

TL;DR: It is demonstrated that retinol-retinl-binding protein and chylomicron remnant retinyl esters in concentrations normally found in human plasma inhibit growth of normal human B lymphocytes, implying that vitamin A present in human Plasma is a normal modulator of B cell function.

TL;DR: RI alpha-RI beta heterodimers complexed with the catalytic subunit represent a novel isozyme of cAKI (RI alpha RI beta C2), which enhances the possibilities for diversification of cAMP-mediated effects.