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Giancarlo Parenti

Researcher at University of Naples Federico II

Publications -  207
Citations -  14701

Giancarlo Parenti is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Enzyme replacement therapy & Ichthyosis. The author has an hindex of 46, co-authored 192 publications receiving 12948 citations. Previous affiliations of Giancarlo Parenti include Baylor College of Medicine.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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A Gene Network Regulating Lysosomal Biogenesis and Function

Marco Sardiello, +13 more
- 24 Jul 2009 - 
TL;DR: It is found that most lysosomal genes exhibit coordinated transcriptional behavior and are regulated by the transcription factor EB (TFEB), providing a potential therapeutic target to enhance cellular clearing in lysOSomal storage disorders and neurodegenerative diseases.
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The Multiple Sulfatase Deficiency Gene Encodes an Essential and Limiting Factor for the Activity of Sulfatases

Maria Pia Cosma, +6 more
- 16 May 2003 - 
TL;DR: The identification, by functional complementation using microcell-mediated chromosome transfer, of a gene that is mutated in MSD and is able to rescue the enzymatic deficiency in patients' cell lines is reported, indicating that SUMF1 is both an essential and a limiting factor for sulfatases.
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Lysosomal Storage Diseases: From Pathophysiology to Therapy

Giancarlo Parenti, +2 more
- 14 Jan 2015 - 
TL;DR: As knowledge has improved about the pathophysiology of lysosomal storage diseases, novel targets for therapy have been identified, and innovative treatment approaches are being developed.
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A cluster of sulfatase genes on xp22.3 : mutations in chondrodysplasia punctata (cdpx) and implications for warfarin embryopathy

Brunella Franco, +13 more
- 07 Apr 1995 - 
TL;DR: The cloned region within Xp22.3 where the CDPX gene has been assigned and three adjacent genes showing highly significant homology to the sulfatase gene family are isolated suggest that warfarin embryopathy might involve drug-induced inhibition of the same enzyme.