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Zuzana Storchova

Researcher at Kaiserslautern University of Technology

Publications -  100
Citations -  10939

Zuzana Storchova is an academic researcher from Kaiserslautern University of Technology. The author has contributed to research in topics: Aneuploidy & Chromosome instability. The author has an hindex of 29, co-authored 88 publications receiving 9398 citations. Previous affiliations of Zuzana Storchova include Harvard University & Charles University in Prague.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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From polyploidy to aneuploidy, genome instability and cancer

TL;DR: A growing amount of evidence indicates that polyploid cells also arise during a variety of pathological conditions, and genetic instability in these cells might provide a route to aneuploidy and thereby contribute to the development of cancer.
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Tetraploidy, aneuploidy and cancer.

TL;DR: Supporting this idea, recent studies demonstrate that tetraploidy promotes chromosomal aberrations and tumorigenesis in vivo, and suggest that there might not be a ploidy-sensing checkpoint that permanently blocks the proliferation of tetraPloid cells.
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Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells

TL;DR: The data present the first broad proteomic analysis of human cells with abnormal karyotypes and suggest a uniform cellular response to the presence of an extra chromosome.
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The consequences of tetraploidy and aneuploidy.

TL;DR: How tetraploidy can occur and the cellular responses to increased ploidy are described are reviewed and the specific physiological changes that are triggered by polyploidization might be used as novel targets for cancer therapy are discussed.